|本期目录/Table of Contents|

[1]欧玲,谢谚,许建和.还原酶催化羰基不对称还原的应用进展[J].生物加工过程,2011,9(02):72-78.[doi:doi:10.3969/j.issn.1672-3678.2011.02.015]
　OU Ling,XIE Yan,XU Jianhe.Advances in application of reductases in carbonyl asymmetric reduction[J].Chinese Journal of Bioprocess Engineering,2011,9(02):72-78.[doi:doi:10.3969/j.issn.1672-3678.2011.02.015]
点击复制

还原酶催化羰基不对称还原的应用进展
(/HTML)
分享到：

《生物加工过程》[ISSN:1672-3678/CN:32-1706/Q]

卷:
9
期数:
2011年02期
页码:
72-78
栏目:
出版日期:
2011-03-30

文章信息/Info

Title:
Advances in application of reductases in carbonyl asymmetric reduction
文章编号:
1672-3678(2011)02-0072-07
作者:
欧玲1; 谢谚2 ; 许建和3
1.河南神马尼龙化工有限责任公司，平顶山 467000；
2.中国石油化工股份有限公司 青岛安全工程研究所，青岛 266071；
3.华东理工大学 生物反应器工程国家重点实验室，上海 200237
Author(s):
OU Ling1; XIE Yan2; XU Jianhe3
1. Henan Shenma Nylon Chemical Co.Ltd.,Pingdingshan 467000,China;
2. SINOPEC Qingdao Safety Engineering Institute,Qingdao 266071,China;
3. State Key Laboratory of Bioreactor Engineering,East China University of Science and Technology,Shanghai 200237,China
关键词:
手性醇; 羰基还原; 不对称还原; 还原酶
分类号:
Q814；TQ463
DOI:
doi:10.3969/j.issn.1672-3678.2011.02.015
文献标志码:
A

参考文献/References:

［1］Yu H L,Xu J H,Lu W Y,et al.Discovery and utilization of biocatalysts for chiral synthesis: an overview of Chinese scientists research and development［J］.Adv Biochem Eng Biotechnol,2009,113:1-31.
［2］张文虎,蔡燕，刘湘,等.芳香酮的不对称还原［J］.化学进展,2007,19(10):1537-1552.
［3］Xie Y,Xu J H,Lu W Y,et al.Adzuki bean: a new resource of biocatalyst for asymmetric reduction of aromatic ketones with high stereoselectivity and substrate tolerance［J］.Biores Technol,2009,100(9):2463-2468.
［4］Liu X,Zhang B L,Xia Y M,et al.Enantioselective reduction of aromatic ketones using celeriac as biocatalyst［J］.Acta Chimica Sinica,2009,67(13):1492-1496.
［5］刘湘,张宝立,夏咏梅,等.植物细胞在含羰基化合物不对称转化中的应用［J］.化学进展,2008,20(7/8):1108-1114.
［6］Tsukiji S,Pattnaik S B,Suga H.An alcohol dehydrogenase ribozyme［J］.Nat Struct Biol,2003,10(9):713-717.
［7］Xie Y,Xu J H,Xu Y.Isolation of a Bacillus strain producing ketone reductase with high substrate tolerance［J］.Biores Technol,2010,101(3):1054-1059.
［8］Itoh N,Matsuda M,Mabuchi M,et al.Chiral alcohol production by NADH-dependent phenylacetaldehyde reductase coupled with in situ regeneration of NADH［J］.Eur J Biochem,2002,269(9):2394-2402.
［9］Patel R N,Chu L,Mueller R.Diastereoselective microbial reduction of (S)-3-chloro-2-oxo-1-(phenylmethyl)propyl］carbamic acid,1,1-dimethylethyl ester［J］.Tetrahedron: Asymmetry,2003,14(20):3105-3109.
［10］Yang W,Xu J H,Xie Y,et al.Asymmetric reduction of aryl ketones with a new isolate Rhodotorula sp.AS2-2241 and synthesis of the β-blocker (R)-nifenalol［J］.Tetrahedron: Asymmetry,2006,17(12): 1769-1774.
［11］Procopiou P A,Morton G E,Todd M,et al.Enantioselective synthesis of (S)-salmeterol via asymmetric reduction of azidoketone by Pichia angusta［J］.Tetrahedon: Asymmetry,2001,12(14): 2005-2008.
［12］Kosjek B,Stampfer W,van Deursen R,et al.Efficient production of raspberry ketone via green biocatalytic oxidation［J］.Tetrahedron,2003,59(48):9517-9521.
［13］Kawano S,Horikawa M,Yasohara Y,et al.Microbial enantioselective reduction of acetylpyridine derivatives［J］.Biosci Biotech Biochem,2003,67(4):809-814.
［14］Haberland J,Hummel W,Daussmann T,et al.New continuous production process for enantiopure (2R,5R)-hexanediol［J］.Org Process Res Dev,2002,6(4):458-462.
［15］Patel R N,Banerjee A,Mcnamee C G,et al.Enantioselective microbial reduction of 3,5-dioxo-6-(benzyloxy) hexanoic acid,ethyl ester［J］.Enzyme Microb Technol,1993,15(12):1014-1021.
［16］Davis C,Grate J,Gray D,et al.Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives：WO，04015132［P］.2004-02-19.
［17］Schmidt E,Ghisalba O,Gygax D,et al.Optimization of a process for the production of (R)-2-hydroxy-4-phenylbutyric acid:an intermediate for inhibitors of angiotensin converting enzyme［J］.J Biotechnol,1992,24(3):315-327.
［18］Tao J H,McGee K.Development of a continuous enzymatic process for the preparation of (R)-3-(4-fluorophenyl)-2-hydroxy propionic acid［J］.Org Process Res Dev,2002,6(4): 520-524.
［19］Fronza G,Fuganti C,Grasselli P,et al.The mode of baker′s yeast transformation of 3-chloropropiophenone and related ketones:synthesis of (2S)-2-2H］propiophenone,(R)-fluoxetine,and (R)-and (S)-fenfluramine［J］.J Org Chem,1991,56(21):6019-6023.
［20］Bare G,Jacques P,Hubert J B,et al.Bioconversion of a L-carnitine precursor in a one- or two-phase system［J］.Appl Biochem Biotechnol,1991,28/29:445-456.
［21］Chenevert R,Genevieve F,Rhlid R B.Asymmetric synthesis of both enantiomers of fluoxetine via microbiological reduction of ethyl benzoylacetate［J］.Tetrahedron,1992,48(33): 6769-6776.
［22］Harris K J,Sih C.Preparation of 2S-(-)-4-amino-2-hydroxybutanoic acid via yeast-catalyzed stereoselective reduction［J］.Biocatalysis and Biotransformation,1992,5(3):195-201.
［23］Patel R N,Banerjee A,Mcnamee C G,et al.Stereoselective reduction of β-keto esters by Geotrichum candidum［J］.Enzyme Microb Technol,1992,14(9): 731-738.
［24］Barieri C,Caruso E D,Arrigo P,et al.Chemo-enzymatic synthesis of (R)- and (S)-3,4-dichlorophenylbutanolide intermediate in the synthesis of sertraline［J］.Tetrahedron: Asymmetry,1999,10(20):3931-3937.
［25］Patel R N,Banerjee A,Mcnamee C G,et al.Preparation of chiral synthon for HIV protease inhibitor: stereoselective microbial reduction of N-protected α-aminochloroketone［J］.Tetrahedron: Asymmetry,1997,8(15): 2547-2552.
［26］De Amici M,De Micheli C,Carrea G,et al.Chemoenzymatic synthesis of chiral isoxazole derivatives［J］.J Org Chem,1989,54(11):2646-2650.
［27］张鹏华，张梁，卢燕，等.Morganella morganii J-8羰基不对称还原酶的分离纯化及性质研究［J］.生物工程学报,2007,23(2): 268-272.
［28］Bhattacharyya M S,Singh A,Banerjee U C.Immobilization of intracellular carbonyl reductase from Geotrichum candidum for the stereoselective reduction of 1-naphthyl ketone［J］.Bioresour Technol,2010,101(6): 1581-1586.
［29］Li N,Ni Y,Sun Z H.Purification and characterization of carbonyl reductase from Candida krusei SW 2026 involved in enantioselective reduction of ethyl 2-oxo-4-phenylbutyrate［J］.J Mol Catal B: Enzym,2010,66(1/2):190-197.
［30］Ni Y,Li C X,Ma H M,et al.Biocatalytic properties of a recombinant aldo-keto reductase with broad substrate spectrum and excellent stereoselectivity［J］.Appl Microb Biotechnol,2010,89(4):1111-1118.
［31］Ye Q,Yan M,Yao Z,et al.A new member of the short-chain dehydrogenases/reductases superfamily: purification,characterization and substrate specificity of a recombinant carbonyl reductase from Pichia stipitis［J］.Bioresour Technol,2009,100(23):6022-6027.
［32］Yamada-Onedera K,Fukui M,Tani Y.Purification and characterization of alcohol dehydrogenase reducing N-benzyl-3-pyrrolidinone from Geotrichum capitatum［J］.J Biosci Bioeng,2007,103(2): 174-178.
［33］Yamada-Onedera K,Takase Y,Tani Y.Purification and characterization of 2-aminoacetophenone reductase of newly isolated Burkholderia sp.YT［J］.J Biosci Bioeng,2007,104(5):416-419.
［34］Soni P,Kansal H,Banerjee U C.Purification and characterization of an enantioselective carbonyl reductase from Candida viswanathii MTCC 5158［J］.Process Biochem,2007,42(12):1632-1640.

相似文献/References:

[1]杨忠华,王玉,曾嵘,等.利用微生物重组技术促进羰基不对称还原研究进展[J].生物加工过程,2009,7(06):8.
　YANG Zhong-hua,WANG Yu,ZENG Rong,et al.Recent progress of asymmetric reduction of ketones with microbial recombinant technology[J].Chinese Journal of Bioprocess Engineering,2009,7(02):8.
[2]黄和,杨忠华,姚善泾.面包酵母催化羰基不对称还原合成手性醇的研究[J].生物加工过程,2004,2(02):52.[doi:10.3969/j.issn.1672-3678.2004.02.010]

备注/Memo

备注/Memo:
收稿日期：2010-05-03
基金项目：国家自然科学基金资助项目（20576055）
作者简介：欧玲(1972—)，女，四川成都人，硕士，工程师，研究方向：生物催化；许建和(联系人)，教授，E-mail:jianhexu@ecust.edu.cn
更新日期/Last Update: