|本期目录/Table of Contents|

[1]张羽飞,吴洪,姜忠义.生物转化中药化学成分的研究进展[J].生物加工过程,2005,3(03):29-32.[doi:10.3969/j.issn.1672-3678.2005.03.006]
 ZHANG Yu-fei,WU Hong,JIANG Zhong-yi.Progress in biotransformation of chemical composition from traditional chinese medicine[J].Chinese Journal of Bioprocess Engineering,2005,3(03):29-32.[doi:10.3969/j.issn.1672-3678.2005.03.006]
点击复制

生物转化中药化学成分的研究进展()
分享到:

《生物加工过程》[ISSN:1672-3678/CN:32-1706/Q]

卷:
3
期数:
2005年03期
页码:
29-32
栏目:
出版日期:
2005-08-30

文章信息/Info

Title:
Progress in biotransformation of chemical composition from traditional chinese medicine
作者:
张羽飞吴洪姜忠义
天津大学, 化工学院, 天津, 300072
Author(s):
ZHANG Yu-fei WU Hong JIANG Zhong-yi
关键词:
中药化学成分生物转化
分类号:
R931.6
DOI:
10.3969/j.issn.1672-3678.2005.03.006
摘要:
生物转化是实现中药现代化的重要途径之一.阐明了生物转化中药化学成分的研究内容和应用范围,讨论了目前存在的问题和解决办法,并对生物转化中药化学成分的发展趋势进行了展望.

参考文献/References:

[1] 杨凌, 何克江. 替代性消化酶在中药研究开发及其生产中的应用 [A]. 北京:中国微生物学会, 2001.78-82.
[2] Archana Giri, Vikas Dhingra, Giri CC. Biotransformations using plant cells, organ cultures and enzyme systems:current trends and future prospects [J]. Biotechnology Advances, 2001(3):175-199.doi:10.1016/S0734-9750(01)00054-4.
[3] Ravishankar GA, Ramachandra RS. Biotechnological production of phyto-pharmaceuticals [J]. Journal of Biochemistry Molecular Biology and Biophysics, 2000(2):73-102.
[4] Josefina Aleu, Isidro González Collado. Biotransformations by Botrytis species [J]. Journal of Molecular Catalysis B:Enzymatic, 2001, (4-6):77-93.
[5] Ramachandra SR, Ravishankar GA. Plant cell cultures:Chemical factories of secondary metabolites [J]. Biotechnology Advances, 2002(2):101-153.doi:10.1016/S0734-9750(02)00007-1.
[6] 杨红亚, 吴少华, 王兴红. 开展中药生物转化研究意义深远 [J]. 中草药, 2004, (12):1321-1324.doi:10.3321/j.issn:0253-2670.2004.12.001.
[7] 宁黎丽. 雷公藤甲素和雷公藤内酯酮的生物转化研究 [D]. 沈阳:沈阳药科大学, 2003.
[8] Ning LL, Han J, Zhang XY. Biotransformation of triptolide and triptonode by cell suspension cultures of Catharanthus roseus [J]. Journal of Asian Natural Products Research, 2004(2):93-97.doi:10.1080/1028602031000135567.
[9] Ning LL, Zhan JX, Qu GQ. Biotransformation of triptolide by Cunninghamella blakesleana [J]. Tetrahedron, 2003, (23):4209-4213.doi:10.1016/S0040-4020(03)00605-7.
[10] Ning LL, Guo HZ, Jiang XM. Biotransformation of triptonide by cell suspension cultures of Platycodon grandiflorum [J]. Pure and Applied Chemistry, 2003, (2-3):389-392.
[11] Ning LL, QU GQ, Ye M. Cytotoxic Biotransformed Products from Triptonide by Aspergillus niger [J]. Planta Medica, 2003(9):804-808.
[12] Deborah AR, Neil CB. Microbial transformation of alkaloids [J]. Current Opinion in Microbiology, 2002(3):274-281.doi:10.1016/S1369-5274(02)00317-X.
[13] Li D, Park SH, Shim JH. In vitro enzymatic modification of puerarin to puerarin glycosides by maltogenic amylase [J]. Carbohydrate Release, 2004, (17):2789-2797.doi:10.1016/j.carres.2004.09.017.
[14] Vladu B, Woynarowski JM, Manikumar G. 7-and 10-Substituted Camptothecins:Dependence of Topoisomerase Ⅰ-DNA Cleavable Complex Formation and Stability on the 7-and 10-Substituents [J]. Molecular Pharmacology, 2000(2):243-251.
[15] Wen Y, Fan Y, Zhang M. Determination of camptothecin and 10-hydroxycamptothecin in human plasma using polymer monolithic in-tube solid phase microextraction combined with high-performance liquid chromatography [J]. Analytical and Bioanalytical Chemistry, 2005.204-210.doi:10.1007/s00216-005-3194-4.
[16] 关水, 安利佳. 喜树碱生物合成途径及其代谢调控的研究进展 [J]. 高技术通讯, 2004, (15):106-110.doi:10.3321/j.issn:1002-0470.2004.05.024.
[17] 朱关平. 用生物转化生产10-羟基喜树碱的方法 [P]. CN:85100520, 1986.
[18] 余伯阳. 生物转化与中药和天然药物创新研究 [A]. 北京:清华大学, 2002.139-141.
[19] 金凤燮. 酶法水解淫羊藿甙糖基制备低糖淫羊藿甙或甙元的方法 [P]. CN:03133635.3, 2004.
[20] Das B, Madhusudhan P, Venkataiah B. Chemoenzymatic transformation of the natural antitumour alkaloid 20-O-acetylcamptothecin to mappicine ketone and(S)-mappicine [J]. Journal of the Indian Chemical Society, 1998, (10-12):662-665.
[21] Dai JG, Yang L, Sakai JI. Combined biotransformations of 4(20), 11-taxadienes [J]. Tetrahedron, 2005, (23):5507-5517.doi:10.1016/j.tet.2005.03.136.
[22] Dai JG, Ye M, Guo HZ. Substrate specificity for the hydroxylation of polyoxygenated 4(20), 11-taxadienes by Ginkgo cell suspension cultures [J]. Bioorganic Chemistry, 2003, (20):345-356.doi:10.1016/S0045-2068(03)00063-4.
[23] Dai JG, Zhang SJ, Sakai JI. Specific oxidation of C-14 oxygenated 4(20), 11-taxadienes by microbial transformation [J]. Tetrahedron Letters, 2003, (20):1091-1094.doi:10.1016/S0040-4039(02)02714-4.
[24] Aberra F, Shu YZ, Zhu MS. Discovering drugs through biological transformation:role of pharmacologically active metabolites in drugs discovery [J]. Journal of Medicinal Chemistry, 2004, (18):4339-4351.doi:10.1021/jm040066v.
[25] 姚新生. 中药天然药物活性成分的研究方法 [J]. 药学服务与研究, 2003(4):205-209.doi:10.3969/j.issn.1671-2838.2003.04.001.

备注/Memo

备注/Memo:
基金项目:教育部跨世纪优秀人才培养计划
更新日期/Last Update: 1900-01-01