|本期目录/Table of Contents|

[1]严明,许伟,陈菲.E.coli天冬氨酸转氨酶结构与功能关系的研究进展[J].生物加工过程,2004,2(03):14.[doi:10.3969/j.issn.1672-3678.2004.03.004]
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E.coli天冬氨酸转氨酶结构与功能关系的研究进展()
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《生物加工过程》[ISSN:1672-3678/CN:32-1706/Q]

卷:
2
期数:
2004年03期
页码:
14
栏目:
出版日期:
2004-08-30

文章信息/Info

Title:
Advances in structure and function of E.coli AspAT
作者:
严明1许伟2陈菲1
1. 南京工业大学, 制药与生命科学学院, 南京, 210009; 2. 南京工业大学, 制药与生命科学学院, 南京, 210009; 盐城工学院, 化学工程系, 盐城, 224003
关键词:
天冬氨酸转氨酶结构基因多态性突变
分类号:
Q814
DOI:
10.3969/j.issn.1672-3678.2004.03.004
摘要:
天冬氨酸转氨酶是转氨反应的高效催化剂,并且对细胞中氮和碳的代谢起到非常重要的作用.上世纪90年代中期以来,从结构的水平上来分析E.coli 天冬氨酸转氨酶的催化机理,以指导酶的改造研究已经成为国外的研究热点.从酶的催化机理、序列及结构特点、活性中心残基组成以及基因多态性对结构和功能的影响四个方面,综述近年来有关E.coli天冬氨酸转氨酶的研究现状.

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备注/Memo

备注/Memo:
基金项目:国家重点基础研究发展计划(973计划)
更新日期/Last Update: 1900-01-01